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Introducing IBRANCE® Tablets

No action is needed on your part—you will continue to receive your prescribed IBRANCE in the same way that you are used to.

See below for notable differences between IBRANCE capsules and IBRANCE tablets.

INDICATIONS: IBRANCE 125 mg capsules or tablets is a prescription medicine used in adults to treat hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) breast cancer that has spread to other parts of the body (metastatic) in combination with an aromatase inhibitor as the first hormonal based therapy in postmenopausal women or in men, or fulvestrant in people with disease progression following hormonal therapy.

Introducing IBRANCE® Tablets

No action is needed on your part—you will continue to receive your prescribed IBRANCE in the same way that you are used to.

See below for notable differences between IBRANCE capsules and IBRANCE tablets.

Here’s What’s Different:

Current Capsule
125mg
100mg
75mg

Must be taken with food

Contains lactose (dairy) and gelatin

Gelatin-coated capsule

Received in bottle; can be stored in bottle or pill caddy

New Tablet
125mg
100mg
75mg

May be taken with or without food

Does not contain lactose or gelatin

Smooth-coated tablet

Received in—and must be stored in—blister packs

Capsules and tablets shown above are not actual size.

Talk to your doctor or pharmacist about any questions you may have.

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FOR LIVE, PERSONALIZED SUPPORT

Call 1-844-9-IBRANCE (Monday–Friday 8 AM–8 PM ET)

FAQ icon

IBRANCE FAQs

Will my dosing schedule stay the same?

Yes, you will continue to take your prescribed dose of IBRANCE on the same schedule: Take 1 IBRANCE tablet, once daily for 21 consecutive days, followed by 7 days off treatment. Remember to continue to take your combination treatment—an aromatase inhibitor or fulvestrant—as instructed by your healthcare provider. Talk to your doctor or pharmacist if you have any questions.

Why is Pfizer making this change from the capsule to the tablet?

The tablet offers you the flexibility to take IBRANCE with or without food.

Is the active ingredient the same?

Yes, the new tablets have the same active ingredient (palbociclib) as the capsules and the same three dosage strengths are available (125 mg, 100 mg, 75 mg).

Why is Pfizer changing from the bottle to the new packaging design?

The IBRANCE tablets need to be stored in the original blister packs. The tablets shouldn’t be removed and placed in a pill caddy. The new packaging features a clear and simple design, with helpful information on how to take once-daily IBRANCE throughout the 3-weeks on, 1-week off treatment schedule. Your monthly box will contain 3 individual weekly packs. Each pack contains 7 IBRANCE tablets.

How should I take IBRANCE tablets?
  • Take IBRANCE exactly as your healthcare provider tells you.
  • IBRANCE tablets may be taken with or without food.
  • IBRANCE should be taken at about the same time each day.
  • Swallow IBRANCE tablets whole. Do not chew, crush, or split IBRANCE tablets before swallowing them.
  • Do not take any IBRANCE tablets that are broken, cracked, or that look damaged.
  • Avoid grapefruit and grapefruit products during treatment with IBRANCE. Grapefruit may increase the amount of IBRANCE in your blood.
  • Do not change your dose or stop taking IBRANCE unless your healthcare provider tells you.
  • If you miss a dose of IBRANCE or vomit after taking a dose of IBRANCE, do not take another dose on that day. Take your next dose at your regular time.
  • If you take too much IBRANCE, call your healthcare provider right away or go to the nearest hospital emergency room.

See Patient Information for IBRANCE tablets to learn more

How should I store IBRANCE tablets?

Store IBRANCE at 68 °F to 77 °F (20 °C to 25 °C) in the original blister pack.

Keep IBRANCE and all medicines out of the reach of children.

Will I continue to get refills of IBRANCE the same way?

Yes, there is no change in access and no action needed on your part. You will continue to receive your IBRANCE the same way.

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Get To Know Women Taking IBRANCE

Gain strength and inspiration from women who’ve been prescribed IBRANCE. Their caregivers have thoughts to share as well. Hear the stories of IBRANCE Ambassadors and learn the ways they’ve adjusted to their new normal.

Ibrance (palbociclib) Ambassador Patti smiling

Get To Know Women Taking IBRANCE

Gain strength and inspiration from women who’ve been prescribed IBRANCE. Their caregivers have thoughts to share as well. Hear the stories of IBRANCE Ambassadors and learn the ways they’ve adjusted to their new normal.

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Turn to Pfizer Oncology Together to learn about financial assistance resources and get personalized support from one of our dedicated Care Champions.

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CALL 1-844-9-IBRANCE (Monday–Friday 8 AM–8 PM ET)